Elevated Urinary CCL2

Obesity Triggers Enhanced MDSC Accumulation in Murine Renal Tumors via Elevated Local Production of CCL2

Obesity is one of the leading risk factors for developing renal cell carcinoma, an immunogenic tumor that is treated clinically with immunostimulatory therapies. Currently, however, the mechanisms linking obesity with renal cancer incidence are unclear. Using a model of diet-induced obesity, we found that obese BALB/c mice with orthotopic renal tumors had increased total frequencies of myeloid-...

Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients

BACKGROUND Sarcoidosis is a granulomatous systemic inflammatory disease in which more than 90 % of all patients develop pulmonary manifestations. Several gene associations have previously been described, but established and clinically useful biomarkers are still absent. This study aimed to find proteins in bronchoalveolar lavage (BAL) fluid that can be associated with the disease. METHODS We ...

CC chemokines CCL2, CCL3, CCL4 and CCL5 are elevated in osteoporosis patients

Elevated antibiotic resistance of Sudanese urinary tract infection bacteria

This study determined the prevalence of urinary tract infections in the Sudanese state of Khartoum and antimicrobial susceptibility pattern of isolated bacterial species. 200 adult patient urine specimens were collected and cultivated to identify the growing bacteria and their susceptibility to antibiotics. 35 % of specimens had significant bacterial growth. The most frequent isolates in this s...

Urinary Angiotensinogen Is Elevated in Patients with Nephrolithiasis

BACKGROUND Elevated urinary angiotensinogen (UA) was identified as novel prognostic biomarker capable of predicting chronic kidney disease, and in the present study, we will investigate the diagnostic value of UA in the patients of nephrolithiasis. METHODS Urine angiotensinogen levels and α 1-microglobulin were measured by enzyme-linked immunosorbent assay (ELISA) in 60 patients presenting wi...